Radiesse vs Sculptra – Which Filler Is Best in Carmel, IN? (2025)

Michele A. Finley, M.D.
October 15, 2025
Radiesse vs Sculptra – Which Filler Is Best in Carmel, IN? (2025)

You look in the mirror one morning and notice your skin doesn’t bounce back like it used to. Maybe your cheeks seem a bit flatter, or those smile lines have settled in deeper. It’s not sudden, but one day it just clicks; you’ve lost some of that youthful volume.



If that sounds familiar, you’re not alone. Facial volume loss happens naturally as collagen and elastin break down with age. The good news is that modern injectables can restore lost volume and stimulate natural collagen production without surgery. Two of the most talked-about treatments are Radiesse and Sculptra; both known for creating subtle, natural-looking results that improve over time.


At Michele Finley, MD Cosmetic Medicine in Carmel, Indiana, board-certified physician Dr. Michele Finley helps patients understand these options and choose the right dermal filler for their goals. With over 20 years of experience in aesthetic medicine, Dr. Finley has refined the art of non-surgical facial rejuvenation, blending science and skill to deliver results that look and feel authentic.


What Are Biostimulatory Fillers?

You’ve probably heard the term before, but what exactly makes biostimulatory fillers different from traditional injectables? Let’s break down the science behind them.


The Science Behind Collagen Stimulation

Traditional dermal fillers made from hyaluronic acid offer instant plumping, but the results fade as the gel dissolves. Biostimulatory fillers, like Radiesse and Sculptra, go further. Instead of just filling space, they stimulate collagen production. This is essentially teaching your body to rebuild its own structural support.


Radiesse contains calcium hydroxylapatite (CaHA) microspheres suspended in a gel. Once injected, the gel offers immediate volume, while the microspheres gradually trigger your body to produce more collagen around them.


Sculptra, on the other hand, is made of poly-L-lactic acid (PLLA), a biodegradable material used in dissolvable sutures. As the PLLA particles break down, they encourage fibroblasts to form new collagen fibers that improve skin thickness and texture over time (Cleveland Clinic, PubMed).


Why Collagen-Stimulating Fillers Are Trending in 2025

More people today want regenerative treatments that do more than disguise wrinkles. They want real, lasting skin improvement. Biostimulatory fillers fit that trend perfectly.


Both Radiesse® and Sculptra® restore volume gradually, reduce fine lines, and improve skin elasticity by boosting your body’s collagen and elastin. They’re popular choices for treating nasolabial folds, jawline contouring, and even non-surgical lower face rejuvenation.


The biggest appeal? The results look natural, because they are natural. You’re not just adding filler, you’re encouraging your skin to rebuild itself.


Radiesse and Sculptra Explained

Radiesse and Sculptra Explained

Before choosing between them, it helps to know what sets these two injectables apart.




Radiesse: Structure and Instant Lift

Radiesse is a dermal filler composed of calcium hydroxylapatite, a mineral-like compound found naturally in human bones. The microspheres are suspended in a water-based gel, which provides immediate lift right after injection.


As time passes, the CaHA stimulates natural collagen production, gradually replacing the gel carrier with your body’s own tissue. Radiesse can also be used to fill deep wrinkles, define the jawline, or correct volume loss in the mid-face and hands.


It’s FDA-approved for treating moderate to severe facial wrinkles and folds, including nasolabial folds, and has a strong reputation for lifting and contouring.


Sculptra: Subtle and Steady Collagen Builder

Sculptra works differently. It doesn’t add instant volume but rather encourages collagen growth over time. The poly-L-lactic acid particles stay active in the skin for months, gradually stimulating collagen and elastin to restore the skin’s framework.


Sculptra is FDA-approved for facial volume restoration and is often used for areas like the temples, cheeks, and lower face. It’s also used off-label for non-surgical buttock enhancement and chest rejuvenation. Because Sculptra works slowly, results appear naturally, typically after a few months of Sculptra injection treatments.


How They Work: Key Mechanisms of Action

The best way to understand Radiesse vs Sculptra is to look at what happens beneath the surface.


Radiesse: Instant Lift, Lasting Structure

When Radiesse injections are placed, the gel provides an instant plump, while the CaHA microspheres form a supportive scaffold for new collagen fibers to grow. Over several months, your body replaces the gel with fresh collagen, maintaining smoothness and firmness for 12 to 18 months.


Sculptra: Gradual Collagen Restoration

Sculptra filler works more like a seed planted beneath your skin. Once injected, the PLLA particles trigger the body’s healing response, encouraging it to produce more collagen. This process is slow and steady, with visible results appearing after a few months and lasting up to two years or more.


Comparison Table: Sculptra® vs Radiesse®

Feature Radiesse® Sculptra®
Main ingredient Calcium Hydroxylapatite (CaHA) Poly-L-lactic acid (PLLA)
Onset of results Immediate Gradual (6–12 weeks)
Duration 12–18 months Up to 24+ months
Ideal candidate Needs lift and structure Needs volume and skin renewal
Treatment sessions Usually one Series of 2–4

Ideal Candidates for Each Filler

Choosing between Radiesse or Sculptra depends on your goals, anatomy, and how quickly you want to see results.


Best Suited for Radiesse

Radiesse offers immediate volume and structure, making it ideal for those who want instant definition. It’s great for facial contouring, jawline sculpting, and cheek enhancement. Both men and women who want a lifted, firmer look often choose Radiesse over other fillers for its fast, visible impact.


Best Suited for Sculptra

If you’re patient and prefer gradual improvement, turn to Sculptra. It’s perfect for those who want subtle rejuvenation and overall improvement in skin tone, texture, and elasticity. Many people love how Sculptra results unfold slowly, creating a refreshed, natural look without the “done” appearance.


When to Combine Both

Some patients benefit from a combined approach. Using Radiesse and Sculptra together can deliver immediate lift with long-term collagen support. Dr. Finley often designs custom plans that use both to stimulate collagen production while restoring youthful balance and symmetry.


The Treatment Experience at Michele Finley, MD Cosmetic Medicine

At Dr. Finley’s Carmel clinic, every injectable treatment starts with a personalized consultation.


Personalized Consultation with Dr. Finley

Dr. Finley evaluates your skin health, facial structure, and goals to create a treatment plan that fits your anatomy and desired outcome. Her experience in both internal medicine and aesthetics allows her to prioritize safety and precision.


Step-by-Step Treatment Process

  1. Preparation: Skin is cleansed and prepped for injection.
  2. Injection: Small amounts of Radiesse filler or Sculptra injections are placed strategically in specific treatment areas.
  3. Aftercare: Mild swelling or redness may occur but fades within a day or two. Patients receiving Sculptra treatment are usually advised to massage the area to help distribute the product evenly.
     

Why Patients Trust Dr. Finley

Dr. Finley’s focus is always on natural outcomes. She understands the nuances of facial volume and how to enhance your best features without changing how you look. Her gentle approach and medical expertise ensure results that are elegant and safe.


Results and Longevity

Wondering how long your glow will last? Let’s look at what you can expect from each treatment.


Radiesse Results (Before/After)

You’ll notice Radiesse results immediately after injection. Over time, collagen remodeling makes the skin firmer and smoother. Most patients enjoy their results for 12–18 months, though touch-ups may extend longevity.

Radiesse Results - Before/After

Visible enhancement of neck firmness and contour following Radiesse injections.


Sculptra Results (Before/After)

Sculptra gradually improves volume and firmness over 2–4 months as collagen production over time rebuilds the skin’s structure. Full results can last up to two years, depending on the number of sessions and lifestyle factors.

Sculptra Results (Before/After)

Before and after Sculptra treatment showing lifted, smoother cheeks with reduced sagging.


Maintaining Results

Hydration, nutrition, and sun protection all support collagen health. Dr. Finley recommends periodic maintenance sessions to sustain results and promote continuous collagen growth.


Potential Side Effects and Safety Considerations

While biostimulatory fillers are generally safe, it’s important to be aware of the minor and rare reactions that can occur.


Common and Temporary Effects

Mild redness, tenderness, or swelling is normal and resolves quickly. Bruising may occur but usually fades within a few days.


Rare Complications

Though uncommon, small bumps or unevenness can develop if fillers are placed incorrectly. This is why Radiesse and Sculptra are effective only when administered by an experienced injector like Dr. Finley.


Safety First

Both Radiesse and Sculptra are FDA-approved, meaning they meet strict safety standards. Dr. Finley’s extensive training ensures that every injection is done with precision, minimizing side effects and ensuring a smooth, natural finish.


Radiesse & Sculptra - Cost and Value Comparison in Carmel, IN (2025)

Treatment Average Price (per session) Duration Sessions Required
Radiesse $700–$900 12–18 months 1 session
Sculptra $800–$1,000 Up to 24 months 2–4 sessions

While Sculptra depends on multiple sessions, it often provides longer-lasting results. Radiesse provides immediate volume and contour with fewer appointments. The right choice depends on your preferences for timing, cost, and longevity.



FAQs About Radiesse and Sculptra

  • 1. How soon will I see results from each filler?

    You’ll see results from Radiesse immediately. Sculptra results appear gradually over 2–3 months as new collagen forms.

  • 2. Can I combine both fillers in one session?

    Yes, many patients do. Combining Radiesse and Sculptra for facial rejuvenation delivers instant lift and long-term collagen stimulation.

  • 3. Are they safe for all skin types?

    Yes. Both fillers are biocompatible and safe across skin tones when performed by a qualified provider.

  • 4. What areas of the face benefit the most?

    Radiesse can be used for the jawline, chin, and cheeks, while Sculptra is also great for temples, lower face, and overall skin improvement.

  • 5. How long do the results last?

    Radiesse results typically last 12–18 months, while Sculptra results can last up to 2 years or more.

Conclusion: Choosing the Right Filler in Carmel, IN

Both Radiesse and Sculptra offer incredible, natural-looking results; but they work differently. If you want an instant lift and visible contouring, choose Radiesse. If you prefer a gradual, subtle improvement in skin texture and volume, turn to Sculptra.



At Michele Finley, MD Cosmetic Medicine, every treatment is personalized. Whether it’s Radiesse treatments, Sculptra aesthetic, or a custom combination plan, Dr. Finley helps you choose the right treatment for your features and goals.


Ready to refresh your look? Schedule a personalized consultation with us today to discover which filler treatment is right for you.

Dr. Michele Finley

Meet Michele Finley, MD, a renowned expert in cosmetic treatments, dedicated to enhancing your beauty and confidence with personalized care and precision.

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